Journal
INFECTION GENETICS AND EVOLUTION
Volume 8, Issue 5, Pages 682-688Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.meegid.2008.06.008
Keywords
Dengue-3 virus; Dengue-3 evolution; Dengue-3 transmission
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Funding
- United States Department of Defense Global Emerging Infections Systems Research Program [847705.82000.25GB.B0016]
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A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru. (C) 2008 Elsevier B.V. All rights reserved.
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