4.4 Article

Emergence of Daptomycin-Resistant VRE: Experience of a Single Institution

Journal

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
Volume 32, Issue 4, Pages 391-394

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1086/659152

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Funding

  1. National Institutes of Health/National Institute of Allergy and Infectious Diseases [MK-K23AI083880]

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Recent surveillance from US hospitals shows that more than 99.5% of vancomycin-resistant enterococci (VRE) isolates remain susceptible to daptomycin. This report describes emergence of daptomycinresistant VRE at a major cancer center. The percentage of patients with daptomycin-resistant VRE bacteremia increased from 3.4% in 2007 to 15.2% in 2009 (Pp. 03). Without susceptibility data, empiric daptomycin therapy for VRE infections should be used with caution. Infect Control Hosp Epidemiol 2011;32(4):391-394

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