4.4 Article

Prospective Comparison of Tuberculin Skin Test and QuantiFERON-TB Gold In-Tube Assay for the Detection of Latent Tuberculosis Infection among Healthcare Workers in a Low-Incidence Setting

Journal

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
Volume 30, Issue 11, Pages 1123-1126

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1086/644754

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Funding

  1. National Institute of Environmental Health Sciences [IAG Y1-E5-0001]

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We compared the results of the tuberculin skin test with the results of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay among 182 low-risk healthcare workers. Overall agreement and specificity were high, but the tests did not agree on positive results. Only 2 of 5 positive QFT-GIT assay results could be confirmed with repeat analyses. Indeterminate results were associated with potential immunosuppression.

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