Journal
INFECTION AND IMMUNITY
Volume 81, Issue 10, Pages 3627-3631Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.00550-13
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Funding
- Japan Society for the Promotion of Science [19380173, 20580338]
- Ministry of Health, Labor and Welfare, Japan
- Grants-in-Aid for Scientific Research [19380173, 23390100, 20580338, 24590516] Funding Source: KAKEN
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Staphylococcal enterotoxins (SEs) are a common causative agent of food poisoning. Recently, many new SE-like (SEl) toxins have been reported, although the role of SEls in food poisoning remains unclear. In this study, the emetic potentials of SElK, SElL, SElM, SElN, SElO, SElP, and SElQ were assessed using a monkey-feeding assay. All the SEls that were tested induced emetic reactions in monkeys at a dose of 100 mu g/kg, although the numbers of affected monkeys were significantly smaller than the numbers that were affected after consuming SEA or SEB. This result suggests that these new SEs may play some role in staphylococcal food poisoning.
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