Journal
INFECTION
Volume 42, Issue 2, Pages 441-444Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s15010-013-0569-x
Keywords
Enteroaggregative Escherichia coli; Extraintestinal infection; Urinary tract infection; Sepsis
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Funding
- Swiss Federal Office for Public Health, National Centre for Enteropathogenic Bacteria and Listeria at the Institute for Food Safety and Hygiene of the University of Zurich
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We report a case of a 55-year-old immunocompromised female who presented to the emergency department with severe diarrhea and vomiting following travel to the Philippines. Stool bacteriology revealed a mixed infection involving an enteropathogenic Escherichia coli and two distinct strains of enteroaggregative Escherichia coli (EAEC). During hospitalization, urine and blood culture tested positive for one of the diarrheagenic EAEC strains, necessitating urinary catheterization, intensive care, and antimicrobial treatment with trimethoprim sulfamethoxazole, followed by meropenem. Although known to occasionally cause urinary tract infections, EAEC have not been previously associated with sepsis. Our report highlights the potential of EAEC to cause severe extraintestinal infections.
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