Valorisation of Mangifera indica crop biomass residues

Mangifera indica L. is one of the most important commercial plants worldwide in terms of production, marketing and consumption. Although the fruit is widely studied, few works focus other vegetal materials, which could be excellent sources of metabolites with potential application in several industries. Additionally, some M. indica varieties remain unstudied. The aim of this work was to explore for the first time the chemical composition and the biological properties of aqueous extracts from M. indica var. Nunkourouni leaf and stem bark. Malic and quinic acids were the most abundant organic acids. Mangiferin and gallic acid were the main phenolics in stem bark and leaves, respectively. A concentration-dependent activity was noticed against several reactive species, stem bark displaying stronger antioxidant capacity. The two materials also inhibit alpha-glucosidase and alpha-amylase, leaves being more potent. The cytotoxic effects on AGS cells were also approached, leaves being the most active material. The results suggest that M. indica leaf and stem bark could be valuable sources of bioactive compounds, contributing to the valorisation of these materials and their further application in high prevalence diseases.