Chemical composition of essential oil and in vitro antioxidant and antimicrobial activities of crude extracts of Commiphora myrrha resin

The antioxidant and antimicrobial potential of methanol (ME-OH), ethyl acetate (ETOAC) crude extracts and essential oil (EO) of Commiphora myrrha resin were investigated. The major con, stituents of the essential oil identified from the resin of C myrrha were a-elemene (12.86%), 7-isopropyl-1,4-dimethyl-2-azulenol (12.22%), curzerene (11.64%), and germacra-1(10)7,11-trien-15-oic acid,8,12-epoxy-6-hydroxy-c-lactone (6.20%). In both DPPH scavenging and Fe2+ chelating assays, the ME-OH extract exhibited the highest activity compared to ETOAC extract and EO. Concerning the reducing power ability. EO was superior to Me-OH and ETOAC extracts. The Me-OH extract manifested the highest potential of antimicrobial activity against the tested bacterial and yeast microorganisms, while ETOAC extract and EO showed moderate or no potential antibacterial activity. The Me-OH extract exhibited the highest antioxidant and antimicrobial activity as compared to ETOAC and EO. It is concluded from the present study that besides its traditional use, the C. myrrha resin could be used as a natural source for antioxidant and antimicrobial compounds for possible applications in food and nutraceutical industries. (C) 2014 Elsevier B.V. All rights reserved.