Journal
INDUSTRIAL CROPS AND PRODUCTS
Volume 49, Issue -, Pages 879-882Publisher
ELSEVIER
DOI: 10.1016/j.indcrop.2013.07.010
Keywords
Pistacia lentiscus L.; Anti-inflammatory activity; Antiulcerogenic activity; Leaves extracts
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Plants have been used for centuries in traditional medicines. In the present study, we investigated in vivo the efficacy of the aqueous and organic extracts from Pistacia lentiscus L leaves for their anti-inflammatory and antiulcerogenic activities using the carrageenan-induced paw edema assay and HCl/ethanol-induced Gastric lesions in rats, respectively. The aqueous (AQ), chloroformic (CHCl3), ethyl acetate (EtOAc) and methanolic (MeOH) leaves extracts (50,100 and 200 mg/kg) given intraperitoneally (i.p.) showed a dose-dependent anti-inflammatory effect. The CHCl3, EtOAc and MeOH leaves extracts when administered orally (p.o), (25,50 and 100 mg/kg), exhibited an inhibition of gastric lesions in a concentration-related manner. The effect of all extracts in both activities were compared with reference drugs. (C) 2013 Elsevier B.V. All rights reserved.
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