Journal
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
Volume 53, Issue 18, Pages 7660-7669Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ie403903q
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Funding
- Indian Council of Medical Research (ICMR) (IRIS) [2010-08660, 5/20/11(Bio)/10-NCD-I]
- Department of Science and Technology, New Delhi, India (DST-TSD) [DST/TSG/NTS/2011/73]
- Department of Science and Technology, New Delhi, India (DST-EMEQ) [SB/EMEQ-185/2013]
- Council of Scientific Industrial Research (CSIR) [01(2547)/11/EMR-II]
- UGC [F.30-1/2013 (SA-II)/RA-2012-14-NEW-SC-TAM-3240, F.30-1/2013(SA-II)/RA-2012-14-NEW-SC-TAM-3228]
- DST [SR/WOS-A/PS-26/2012 (G)]
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Hydroxyapatite (HAP) is the most suitable nontoxic, biocompatible material increasingly used for bone implant coatings. However, its brittle nature is a major obstacle for such applications and this leads to the focus on developing composite coatings with the incorporation of various biopolymers and reinforcing material. In this study, mineral-substituted hydroxyapatite (M-HAP) and carboxymethyl chitosan (CMC), a biopolymer, are made into a composite (CMC/M-HAP) for enhanced biological properties of HAP. Furthermore, carbon nanotubes (CNTs) are incorporated in the composite to improve the mechanical and anticorrosive properties of HAP. The present work investigates the development of CNTs/CMC/M-HAP composite coating on piranha-treated Ti-6Al-4V alloy for improved biological and mechanical properties, which is anticipated to be the most suited alternative material for orthopedic implants.
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