Journal
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 75, Issue 1, Pages 3-10Publisher
INDIAN PHARMACEUTICAL ASSOC
DOI: 10.4103/0250-474X.113529
Keywords
Angiogenesis; cancer; inhibitors of angiogenesis; small molecules
Categories
Ask authors/readers for more resources
Recent advances in cancer research highlighted the importance of target-specific drug discovery. In view of these advances, the most important mechanism in tumour growth is its ability to stimulate the formation of blood capillaries around itself called tumour-driven angiogenesis. Hence targeting the angiogenesis, inhibits the growth of blood vessels around it and responsible for death of the tumour due to starvation and accumulation of toxic waste. The therapy, thus, indirectly cytotoxic to the tumour cells by targeting newly developing blood vessels. In this review, we summarised the various antiangiogenic agents with their clinical uses and current status.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available