Journal
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 71, Issue 2, Pages 139-142Publisher
INDIAN PHARMACEUTICAL ASSOC
DOI: 10.4103/0250-474X.54280
Keywords
Curcumin; dissolution medium; sodium lauryl sulphate
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Funding
- Natural Remedies Pvt. Ltd, Bangalore
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Curcumin is a phytoconstituent with wide range of biological activity. It is poorly soluble in water. In the present study a new dissolution medium was developed, as there is no validated dissolution method available in the literature. The composition of the dissolution medium was selected on the basis of solubility data at 37. Solubility data revealed that addition of surfactant may be suitable as a dissolution medium. The suitability of dissolution medium (0.5 sodium lauryl sulphate in water) relative to the other dissolution medium was evaluated. The selected dissolution media was used for the evaluation of curcumin tablets.
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