Journal
IMMUNOLOGY LETTERS
Volume 162, Issue 2, Pages 95-102Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.imlet.2014.10.010
Keywords
Innate immune response; Cellular and humoral branch; Neuronal regulation; Granulocytes; Complement system; Macrophages
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Funding
- Netherlands Organization for Scientific Research (NWO) [053.21.112]
- Dutch Kidney Foundation
- Lung Foundation Netherlands [3.2.10.052]
- Dutch Foundation [COS21012]
- German Cystic Fibrosis Foundation [COS21012]
- European Union [1209]
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The innate immune response is of prime importance in the immediate recognition and elimination of invading micro-organisms. However, deregulation of this system is clearly associated with the pathogenesis of a wide range of inflammatory diseases. Innate immunity consists of a humoral and a cellular branch, which are closely interacting. An additional level of control is found at the level of neuronal reflexes that can fine-tune these immunological mechanisms. (C) 2014 Elsevier B.V. All rights reserved.
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