Journal
IMMUNOLOGY LETTERS
Volume 126, Issue 1-2, Pages 83-84Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.imlet.2009.08.004
Keywords
Hemocyte; Hemocyte marker; In vivo; Lamellocyte; Drosophila; Differentiation
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Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific immunological markers. Here we suggest that an MiET1 GFP-reporter element insertion in the untranslated region of a gene (l1-atilla) - expressed in a subset of hemocytes, the lamellocytes - allows in vivo investigations of lamellocyte differentiation and facilitates genetic screens. (C) 2009 Elsevier B.V. All rights reserved.
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