Journal
IMMUNOLOGY AND CELL BIOLOGY
Volume 91, Issue 4, Pages 263-270Publisher
WILEY
DOI: 10.1038/icb.2012.76
Keywords
cutaneous immunity; dendritic cells; intravital imaging; infectious disease; neutrophils
Categories
Funding
- NHMRC
- ARC
Ask authors/readers for more resources
The skin is under constant assault by environmental factors and microbes. Innate immune cells in epidermis and dermis regulate immune responses against pathogens while maintaining tolerance against commensal bacteria and autoantigens. The introduction of intravital imaging approaches, in particular multiphoton microscopy, has enabled studying the cellular and molecular regulation of cutaneous immunity in real time within intact skin. Here, we discuss recent advances in our understanding of innate immune cell behaviour in the skin, as unravelled by intravital microscopy, with emphasis on the function of myeloid cells, including dendritic cells, neutrophils and monocytes. Immunology and Cell Biology (2013) 91, 263-270; doi:10.1038/icb.2012.76; published online 5 March 2013
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available