Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 34, Issue 1, Pages 33-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2013.09.012
Keywords
Chronic urticaria; Mast cells; Basophils
Categories
Funding
- Novartis
- Genentech
- Astra Zeneca
- National Institutes of Health
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Urticaria affects individuals of all ages and is commonplace. Nearly 1 in 5 individuals will experience an episode of urticaria in their lifetime, while the chronic form of disease has an estimated annual prevalence of approximately 1% of the population. Given the similarity of chronic urticaria symptoms to those seen in patients suffering an allergic reaction, the condition often leads to a search for an external cause. In most cases, no external trigger factor is identified. At present several theories of pathogenesis exist, none of which is firmly established.
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