Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 32, Issue 4, Pages 587-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2012.08.001
Keywords
Pulmonary vasculitis; Diffuse alveolar hemorrhage; ANCA-associated vasculitis; Granulomatosis with polyangiitis; Microscopic polyangiitis; Eosinophilic granulomatosis with polyangiitis
Categories
Funding
- Genentech/BiogenIDEC
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Diffuse alveolar hemorrhage is a clinical syndrome that can be a manifestation of multiple different causes. Identification of the underlying etiology is of utmost importance and dictates treatment. Pulmonary vasculitis including antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a common cause of diffuse alveolar hemorrhage. For MV, treatment includes induction followed by maintenance therapy. Rituximab has an increasing role in the treatment of AAV.
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