Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 29, Issue 2, Pages 381-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2009.02.011
Keywords
Innate immunity; Exercise; Macrophages
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Exercise has beneficial effects on chronic disease, and the drive to understand the mechanisms of these benefits is strong. This article presents several compelling potential mechanisms for the anti-inflammatory effect of exercise, including reduced percentage of body fat and macrophage accumulation in adipose tissue, muscle-released interleukin-6 inhibition of tumor necrosis factor-a, and the cholinergic anti-inflammatory pathway.
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