4.6 Article

The formation of P particle increased immunogenicity of norovirus P protein

Journal

IMMUNOLOGY
Volume 136, Issue 1, Pages 28-29

Publisher

WILEY-BLACKWELL
DOI: 10.1111/j.1365-2567.2012.03555.x

Keywords

antigen presentation; calicivirus; norovirus; P domain; P particle; vaccine; vaccine platform

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Funding

  1. NIAID NIH HHS [R01 AI089634] Funding Source: Medline

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As a commentary on a recently published paper in Immunology, this article summaries the principle of norovirus P particle as a promising vaccine against noroviruses. It emphasizes the importance of P particle formation in the immune enhancement of the vaccine and methods for production/verification of high quality P particles which may be easily neglected by researchers.

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