4.6 Review

Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers

Related references

Note: Only part of the references are listed.
Article Immunology

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot et al.

JOURNAL OF IMMUNOLOGY (2017)

Review Biochemistry & Molecular Biology

Vitamin A and immune regulation: Role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance

Barbara Cassani et al.

MOLECULAR ASPECTS OF MEDICINE (2012)

Review Immunology

Regulatory T cells in stem cell transplantation: strategies and first clinical experiences

Matthias Edinger et al.

CURRENT OPINION IN IMMUNOLOGY (2011)

Review Immunology

Oral tolerance

Howard L. Weiner et al.

IMMUNOLOGICAL REVIEWS (2011)

Review Immunology

Regulatory T cells and Foxp3

Alexander Y. Rudensky

IMMUNOLOGICAL REVIEWS (2011)

Article Gastroenterology & Hepatology

Therapy with anti-TNF alpha Antibody Enhances Number and Function of Foxp(3+) Regulatory T Cells in Inflammatory Bowel Diseases

Gilles Boschetti et al.

INFLAMMATORY BOWEL DISEASES (2011)

Review Immunology

CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

S. Alice Long et al.

JOURNAL OF IMMUNOLOGY (2011)

Article Medicine, General & Internal

Coeliac disease and gluten sensitivity

R. Troncone et al.

JOURNAL OF INTERNAL MEDICINE (2011)

Article Multidisciplinary Sciences

Peripheral education of the immune system by colonic commensal microbiota

Stephanie K. Lathrop et al.

NATURE (2011)

Review Multidisciplinary Sciences

Intestinal homeostasis and its breakdown in inflammatory bowel disease

Kevin J. Maloy et al.

NATURE (2011)

Review Medicine, General & Internal

MEDICAL PROGRESS Ulcerative Colitis

Silvio Danese et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Gastroenterology & Hepatology

Increase of regulatory T cells in ileal mucosa of untreated pediatric Crohn's disease patients

Dag Henrik Reikvam et al.

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2011)

Article Multidisciplinary Sciences

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Koji Atarashi et al.

SCIENCE (2011)

Review Immunology

Environmental influences on T regulatory cells in inflammatory bowel disease

Gijs Hardenberg et al.

SEMINARS IN IMMUNOLOGY (2011)

Review Immunology

Moving to tolerance: Clinical application of T regulatory cells

Alicia N. McMurchy et al.

SEMINARS IN IMMUNOLOGY (2011)

Review Immunology

Intestinal CD103+ dendritic cells: master regulators of tolerance?

Charlotte L. Scott et al.

TRENDS IN IMMUNOLOGY (2011)

Review Biochemistry & Molecular Biology

Balancing acts: the role of TGF-β in the mucosal immune system

Joanne E. Konkel et al.

TRENDS IN MOLECULAR MEDICINE (2011)

Article Gastroenterology & Hepatology

Intestinal microbiota in inflammatory bowel disease: Friend of foe?

Francesca Fava et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

IL-15 modulates the effect of retinoic acid, promoting inflammation rather than oral tolerance to dietary antigens

Eduardo Arranz et al.

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2011)

Review Immunology

Phenotypical and functional specialization of FOXP3+ regulatory T cells

Daniel J. Campbell et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Review Immunology

Infectious tolerance: therapeutic potential

Adrian R. Kendal et al.

CURRENT OPINION IN IMMUNOLOGY (2010)

Article Immunology

Immunomodulation by Commensal and Probiotic Bacteria

Paul Forsythe et al.

IMMUNOLOGICAL INVESTIGATIONS (2010)

Article Gastroenterology & Hepatology

TLR5 Is Not Required for Flagellin-mediated Exacerbation of DSS Colitis

Sabine M. Ivison et al.

INFLAMMATORY BOWEL DISEASES (2010)

Article Immunology

Foxp3(+) Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

Nicola Eastaff-Leung et al.

JOURNAL OF CLINICAL IMMUNOLOGY (2010)

Article Medicine, Research & Experimental

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

Pervinder Sagoo et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Medicine, Research & Experimental

Identification of a B cell signature associated with renal transplant tolerance in humans

Kenneth A. Newell et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Review Immunology

Regulatory Lymphocytes and Intestinal Inflammation

Ana Izcue et al.

ANNUAL REVIEW OF IMMUNOLOGY (2009)

Review Immunology

Plasticity of CD4(+) FoxP3(+) T cells

Xuyu Zhou et al.

CURRENT OPINION IN IMMUNOLOGY (2009)

Article Gastroenterology & Hepatology

Smad7 Controls Resistance of Colitogenic T Cells to Regulatory T Cell-Mediated Suppression

Massimo C. Fantini et al.

GASTROENTEROLOGY (2009)

Review Immunology

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

Ethan M. Shevach

IMMUNITY (2009)

Review Immunology

Regulatory T cells: how do they suppress immune responses?

Shimon Sakaguchi et al.

INTERNATIONAL IMMUNOLOGY (2009)

Review Medicine, General & Internal

Coeliac disease

Antonio Di Sabatino et al.

LANCET (2009)

Article Multidisciplinary Sciences

Expression of GARP selectively identifies activated human FOXP3+regulatory T cells

Rui Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Gastroenterology & Hepatology

Increased FOXP3 expression in small-bowel mucosa of children with coeliac disease and type I diabetes mellitus

Tamara Vorobjova et al.

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2009)

Article Immunology

Is FOXP3 a bona fide marker for human regulatory T cells?

Maria-Grazia Roncarolo et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2008)

Review Immunology

How regulatory T cells work

Dario A. A. Vignali et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Article Multidisciplinary Sciences

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

Lauren W. Collison et al.

NATURE (2007)

Review Multidisciplinary Sciences

Unravelling the pathogenesis of inflammatory bowel disease

R. J. Xavier et al.

NATURE (2007)

Article Multidisciplinary Sciences

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

Daniel Mucida et al.

SCIENCE (2007)

Article Gastroenterology & Hepatology

Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+T cells to proliferate and secrete interferon-γ

Iris Dotan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)

Article Multidisciplinary Sciences

Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients

Melinda Raki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Gastroenterology & Hepatology

Expression and functional characterization of FOXP3+CD4+ regulatory T cells in ulcerative colitis

Qi T. Yu et al.

INFLAMMATORY BOWEL DISEASES (2007)

Article Immunology

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

Weihong Liu et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2006)

Article Medicine, Research & Experimental

Defective regulatory and effector T cell functions in patients with FOXP3 mutations

Rosa Bacchetta et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Biochemical Research Methods

De novo production of antigen-specific suppressor cells in vivo

Karsten Kretschmer et al.

NATURE PROTOCOLS (2006)

Article Gastroenterology & Hepatology

A phase I trial with Transgenic bacteria expressing interleukin-10 in Crohn's disease

Henri Braat et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Multidisciplinary Sciences

Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation

SH Rhee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Gastroenterology & Hepatology

Peripheral and intestinal regulatory CD4+CD25high T cells in inflammatory bowel disease

J Maul et al.

GASTROENTEROLOGY (2005)

Article Immunology

T cells that cannot respond to TGF-β escape control by CD4+CD25+ regulatory T cells

L Fahlén et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2005)

Review Gastroenterology & Hepatology

IL-10 and its related cytokines for treatment of inflammatory bowel disease

Ming-Cai Li et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2004)

Article Medicine, Research & Experimental

Bacterial flagellin is a dominant antigen in Crohn disease

MJ Lodes et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Review Immunology

The immunological and genetic basis of inflammatory bowel disease

G Bouma et al.

NATURE REVIEWS IMMUNOLOGY (2003)

Article Immunology

Cutting edge:: Cure of colitis by CD4+ CD25+ regulatory T cells

C Mottet et al.

JOURNAL OF IMMUNOLOGY (2003)

Article Immunology

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

JD Fontenot et al.

NATURE IMMUNOLOGY (2003)