Related references
Note: Only part of the references are listed.The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
Arash Grakoui et al.
JOURNAL OF IMMUNOLOGY (2015)
αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities
Anastasia N. Tikhonova et al.
IMMUNITY (2012)
Structural and biophysical determinants of aß T-cell antigen recognition
John S. Bridgeman et al.
IMMUNOLOGY (2012)
Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4
Yiyuan Yin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Escape from highly effective public CD8+ T-cell clonotypes by HIV
Maria Candela Iglesias et al.
BLOOD (2011)
CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I
Vasily Rybakin et al.
EMBO REPORTS (2011)
Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination
Ning Jiang et al.
IMMUNITY (2011)
Anti-CD8 Antibodies Can Trigger CD8+ T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide-MHCI Tetramer Staining
Mathew Clement et al.
JOURNAL OF IMMUNOLOGY (2011)
The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells
Bruno Laugel et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2011)
Plasticity of human CD8αα binding to peptide-HLA-A*2402
Yi Shi et al.
MOLECULAR IMMUNOLOGY (2011)
CD8 Controls T Cell Cross-Reactivity
Linda Wooldridge et al.
JOURNAL OF IMMUNOLOGY (2010)
MHC Class I Molecules with Superenhanced CD8 Binding Properties Bypass the Requirement for Cognate TCR Recognition and Nonspecifically Activate CTLs
Linda Wooldridge et al.
JOURNAL OF IMMUNOLOGY (2010)
T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility
Oleg Y. Borbulevych et al.
IMMUNITY (2009)
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
Jennifer D. Stone et al.
IMMUNOLOGY (2009)
Structural Basis of the CD8αβ/MHC Class I Interaction: Focused Recognition Orients CD8β to a T Cell Proximal Position
Rui Wang et al.
JOURNAL OF IMMUNOLOGY (2009)
Cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding
David K. Cole et al.
MOLECULAR IMMUNOLOGY (2008)
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor
Angel Varela-Rohena et al.
NATURE MEDICINE (2008)
Deletion of CD4 and CD8 coreceptors permits generation of αβT cells that recognize antigens independently of the MHC
Frangois Van Laethem et al.
IMMUNITY (2007)
A constant affinity threshold for T cell tolerance
Dieter Naeher et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties
Bruno Laugel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region
Linda Wooldridge et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Human TCR-Binding affinity is governed by MHC class restriction
David K. Cole et al.
JOURNAL OF IMMUNOLOGY (2007)
How a single T cell receptor recognizes both self and foreign MHC
Leremy A. Colf et al.
CELL (2007)
CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions
Bruno Laugel et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Disruption of extracellular interactions impairs T cell receptor-CD3 complex stability and signaling
Michael S. Kuhns et al.
IMMUNITY (2007)
Computcational design and crystal structure of an enhanced affinity mutant human CD8 alpha alpha coreceptor
David K. Cole et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Altered peptide Ligands induce delayed CD8-T cell receptor interaction - a role for CD8 in distinguishing antigen quality
Pia P. Yachi et al.
IMMUNITY (2006)
Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers
Linda Wooldridge et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Structural and mutational analyses of a CD8αβ heterodimer and comparison with the CD8αα homodimer
HC Chang et al.
IMMUNITY (2005)
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface
L Wooldridge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand
RL Davis-Harrison et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
NA Borg et al.
NATURE IMMUNOLOGY (2005)
Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition
B Laugel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
T cell receptor-ligand interactions: A conformational preequilibrium or an induced fit
DM Gakamsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Anti-CD8 antibodies can inhibit or enhance Peptide-MHC class I (pMHCI) multimer binding: This is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface
L Wooldridge et al.
JOURNAL OF IMMUNOLOGY (2003)
A correlation between TCR Vα docking on MHC and CD8 dependence:: Implications for T cell selection
J Buslepp et al.
IMMUNITY (2003)
The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities
SL Hutchinson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
PD Holler et al.
IMMUNITY (2003)
Human CD8 co-receptor is strictly involved in MHC-peptide tetramer-TCR binding and T cell activation
R Campanelli et al.
INTERNATIONAL IMMUNOLOGY (2002)
CD8 binding to MHC class I molecules is influenced by maturation and T cell glycosylation
MA Daniels et al.
IMMUNITY (2001)
T cell responses modulated through interaction between CD8αα and the nonclassical MHC class I molecule, TL
AJ Leishman et al.
SCIENCE (2001)
CD8β endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56lck complexes
A Arcaro et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Intraepithelial lymphocytes: exploring the Third Way in immunology
A Hayday et al.
NATURE IMMUNOLOGY (2001)
CD8- T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation
PD Holler et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor ζ chain
MA Purbhoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-Peptide tetramers to TCR
G Denkberg et al.
JOURNAL OF IMMUNOLOGY (2001)
Crystal structure of a T cell receptor bound to an allogeneic MHC molecule
JB Reiser et al.
NATURE IMMUNOLOGY (2000)
Essential role of CD8 palmitoylation in CD8 coreceptor function
A Arcaro et al.
JOURNAL OF IMMUNOLOGY (2000)
Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8αα
GF Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Role of CD8β domains in CD8 coreceptor function:: Importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus
R Bosselut et al.
IMMUNITY (2000)
CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen
D Vremec et al.
JOURNAL OF IMMUNOLOGY (2000)