Related references
Note: Only part of the references are listed.Wiskott-Aldrich syndrome: a comprehensive review
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p53-cofactor JMY is a multifunctional actin nucleation factor
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Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis
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Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets
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Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers
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JOURNAL OF CELL BIOLOGY (2008)
Analysis of WASp function during the wound inflammatory response - live-imaging studies in zebrafish larvae
Ana Cvejic et al.
JOURNAL OF CELL SCIENCE (2008)
Expression of Wiskott-Aldrich syndrome protein in dendritic cells regulates synapse formation and activation of naive CD8+ T cells
Julian Pulecio et al.
JOURNAL OF IMMUNOLOGY (2008)
Hierarchical Regulation of WASP/WAVE Proteins
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Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering
Philipp Mueller et al.
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The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency
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NATURE IMMUNOLOGY (2008)
Mammalian Rho GTPases:: new insights into their functions from in vivo studies
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Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells
Hee-Don Chae et al.
BLOOD (2008)
Long-term outcome following hematopoietic stem-cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and European Group for Blood and Marrow Transplantation
Hulya Ozsahin et al.
BLOOD (2008)
Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells
Gerben Bouma et al.
BLOOD (2007)
Human subtelomeric WASH genes encode a new subclass of the WASP family
Elena V. Linardopoulou et al.
PLOS GENETICS (2007)
Wiskott-Aldrich syndrome protein is a key regulator of the phagocytic cup formation in macrophages
Shigeru Tsuboi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia
Benjamin T. Kile et al.
BLOOD (2007)
Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development
Vinicius Cotta-de-Almeida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia
Dale A. Moulding et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome
Marsilio Adriani et al.
CLINICAL IMMUNOLOGY (2007)
Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL
Maria K. Vartiainen et al.
SCIENCE (2007)
Opposing effects of PKCθ and WASp on symmetry breaking and relocation of the immunological synapse
Tasha N. Sims et al.
CELL (2007)
RhoH is important for positive thymocyte selection and T-cell receptor signaling
Tatjana Dorn et al.
BLOOD (2007)
Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization
Juying Li et al.
NATURE CELL BIOLOGY (2007)
Requirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophages
Shigeru Tsuboi
JOURNAL OF IMMUNOLOGY (2007)
The Wiskott-Aldrich syndrome protein is required for the function of CD4+CD25+Foxp3+ regulatory T cells
Michel H. Maillard et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
WASP regulates suppressor activity of human and murine CD4+CD25+FOXP3+ natural regulatory T cells
Francesco Marangoni et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP)
Akihiro Konno et al.
INTERNATIONAL IMMUNOLOGY (2007)
Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis
Stephanie Humblet-Baron et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP)
Miguel A. de la Fuente et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus
Joseph M. Miano et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
WIP regulates the stability and localization of WASP to podosomes in migrating dendritic cells
Hsiu-Chuan Chou et al.
CURRENT BIOLOGY (2006)
Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients
Sara Trifari et al.
JOURNAL OF IMMUNOLOGY (2006)
RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development
Yi Gu et al.
NATURE IMMUNOLOGY (2006)
Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1
William M. Brieher et al.
JOURNAL OF CELL BIOLOGY (2006)
Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia
Phil J. Ancliff et al.
BLOOD (2006)
The ARP2/3 complex: an actin nucleator comes of age
Erin D. Goley et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis
Niko Foeger et al.
SCIENCE (2006)
Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils
Hong Zhang et al.
IMMUNITY (2006)
Sleeping beauty transposon-based phenotypic analysis of mice:: Lack of Arpc3 results in defective trophoblast outgrowth
Kojiro Yae et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment
Siham Sabri et al.
BLOOD (2006)
Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: A coordinated mechanism for severing and capping filaments
Kyoko Okada et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
RhoG regulates the neutrophil NADPH oxidase
Alison M. Condliffe et al.
JOURNAL OF IMMUNOLOGY (2006)
The Wiskott-Aldrich syndrome
HD Ochs et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells
A Olivier et al.
MOLECULAR THERAPY (2006)
Leukocyte-specific protein 1 (LSP1) - A regulator of leukocyte emigration in inflammation
Jenny Jongstra-Bilen et al.
IMMUNOLOGIC RESEARCH (2006)
Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome
A Cianferoni et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
Genotype-proteotype linkage in the Wiskott-Aldrich syndrome
MI Lutskiy et al.
JOURNAL OF IMMUNOLOGY (2005)
CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism
PC Fulkerson et al.
BLOOD (2005)
WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo
SB Snapper et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2005)
Cortical actin turnover during cytokinesis requires myosin II
M Guha et al.
CURRENT BIOLOGY (2005)
Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways
D Carstanjen et al.
JOURNAL OF IMMUNOLOGY (2005)
RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells
Y Gu et al.
BLOOD (2005)
Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein
S de Noronha et al.
BLOOD (2005)
Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response
L Westerberg et al.
BLOOD (2005)
Phenotypic perturbation of B cells in the Wiskott-Aldrich syndrome
JY Park et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2005)
Early deficit of lymphocytes in Wiskott-Aldrich syndrome: possible role of WASP in human lymphocyte maturation
JY Park et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
Maturation of DC is associated with changes in motile characteristics and adherence
S Burns et al.
CELL MOTILITY AND THE CYTOSKELETON (2004)
Lymphocyte microvilli are dynamic, actin-dependent structures that do not require Wiskott-Aldrich syndrome protein (WASp) for their morphology
S Majstoravich et al.
BLOOD (2004)
Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependent
A Selvaraj et al.
BMC MOLECULAR BIOLOGY (2004)
Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology
A Ruusala et al.
FEBS LETTERS (2004)
Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production
JL Cannon et al.
JOURNAL OF IMMUNOLOGY (2004)
Mutations of the Wiskott-Aldfich syndrome protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation
YZ Jin et al.
BLOOD (2004)
Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect
A Gismondi et al.
BLOOD (2004)
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils
MD Filippi et al.
NATURE IMMUNOLOGY (2004)
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles
A Yamauchi et al.
JOURNAL OF IMMUNOLOGY (2004)
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs
C Borg et al.
BLOOD (2004)
Immunological function in mice lacking the Rac-related GTPase RhoG
E Vigorito et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
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SCIENCE (2003)
Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling
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SCIENCE (2003)
A defect in hematopoietic stem cell migration explains the nonrandorn X-chromosome inactivation in carriers of Wiskott-Aldrich syndrome
C Lacout et al.
BLOOD (2003)
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility
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EMBO JOURNAL (2003)
Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott-Aldrich syndrome protein
L Westerberg et al.
IMMUNOLOGY (2003)
Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading
H Chen et al.
IMMUNITY (2003)
Autoimmunity in Wiskott-Aldrich syndrome: Risk factors, clinical features, and outcome in a single-center cohort of 55 patients
S Dupuis-Girod et al.
PEDIATRICS (2003)
Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice
SH Soderling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
X-linked thrombocytopenia caused by a mutation in the Wiskott-Aldrich syndrome (WAS) gene that disrupts interaction with the WAS protein (WASP)-interacting protein (WIP)
JN Luthi et al.
EXPERIMENTAL HEMATOLOGY (2003)
The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse
K Badour et al.
IMMUNITY (2003)
Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes
B Leader et al.
NATURE CELL BIOLOGY (2002)
Structure of the N-WASP EVH1 domain-WIP complex: Insight into the molecular basis of Wiskott-Aldrich Syndrome
BF Volkman et al.
CELL (2002)
Xenopus actin-interacting protein 1 (XAip1) enhances cofilin fragmentation of filaments by capping filament ends
K Okada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses
JS Orange et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation
L Dupré et al.
IMMUNITY (2002)
Restoration of podosomes and chemotaxis in Wiskott-Aldrich syndrome macrophages following induced expression of WASp
GE Jones et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes
BA Croker et al.
JOURNAL OF IMMUNOLOGY (2002)
Deficiency of small GTPase Rac2 affects T cell activation
H Yu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility
SB Snapper et al.
NATURE CELL BIOLOGY (2001)
Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes
L Westerberg et al.
BLOOD (2001)
Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation
S Burns et al.
BLOOD (2001)
Myosin II dynamics and cortical flow during contractile ring formation in Dictyostelium cells
S Yumura
JOURNAL OF CELL BIOLOGY (2001)
Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency
Y Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
FC Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Cutting edge: The Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells
Y Leverrier et al.
JOURNAL OF IMMUNOLOGY (2001)
Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia
K Devriendt et al.
NATURE GENETICS (2001)
Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages
Y Leverrier et al.
CURRENT BIOLOGY (2001)
Human lymphocyte-specific protein 1, the protein overexpressed in neutrophil actin dysfunction with 47-kDa and 89-kDa protein abnormalities (NAD 47/89), has multiple F-actin binding domains
QH Zhang et al.
JOURNAL OF IMMUNOLOGY (2000)
A chemokine-driven positive feedback loop organizes lymphoid follicles
KM Ansel et al.
NATURE (2000)
Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation
BY Li et al.
SCIENCE (2000)
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
DR Ambruso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)