4.6 Review

IKK biology

Related references

Note: Only part of the references are listed.
Review Immunology

NF-κB function in B lymphocytes

Mary Kaileh et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

IκB kinase regulation of the TPL-2/ERK MAPK pathway

Thorsten Gantke et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out

Kevin W. McCool et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

Regulation of NF-κB by ubiquitination and degradation of the IκBs

Naama Kanarek et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

NF-κB regulation: lessons from structures

Gourisankar Ghosh et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

It takes two to tango: IκBs, the multifunctional partners of NF-κB

Michael Hinz et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

Regulation of NF-κB by deubiquitinases

Edward W. Harhaj et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis

Jonathan K. Chan et al.

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

The noncanonical NF-κB pathway

Shao-Cong Sun

IMMUNOLOGICAL REVIEWS (2012)

Review Immunology

NF-κB and the link between inflammation and cancer

Joseph A. DiDonato et al.

IMMUNOLOGICAL REVIEWS (2012)

Article Multidisciplinary Sciences

Crystal structure of inhibitor of κB kinase β

Guozhou Xu et al.

NATURE (2011)

Article Multidisciplinary Sciences

Tumor suppressor protein (p)53, is a regulator of NF-κB repression by the glucocorticoid receptor

Samantha H. Murphy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

IKK alpha negatively regulates IRF-5 function in a MyD88-TRAF6 pathway

Mumtaz Yaseen Balkhi et al.

CELLULAR SIGNALLING (2010)

Article Biochemistry & Molecular Biology

Neuroprotective potential of the NF-κB inhibitor peptide IKK-NBD in cerebral ischemia-reperfusion injury

Abhishek Desai et al.

NEUROCHEMISTRY INTERNATIONAL (2010)

Article Multidisciplinary Sciences

Loss of p53 enhances catalytic activity of IKKβ through O-linked β-N-acetyl glucosamine modification

Keiko Kawauchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP

Yifeng Xia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Phosphorylation of SNAP-23 by IκB kinase 2 regulates mast cell degranulation

Kotaro Suzuki et al.

Review Biochemistry & Molecular Biology

Shared principles in NF-κB signaling

Matthew S. Hayden et al.

Article Multidisciplinary Sciences

IKKα is a critical coregulator of a Smad4-independent TGFβ-Smad2/3 signaling pathway that controls keratinocyte differentiation

Pascal Descargues et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site

Mia Rushe et al.

STRUCTURE (2008)

Article Immunology

Inhibition of NF-κB activation reduces the tissue effects of transgenic IL-13

Svetlana P. Chapoval et al.

JOURNAL OF IMMUNOLOGY (2007)

Article Multidisciplinary Sciences

A role for IκB kinase 2 in bipolar spindle assembly

Jeffrey T. Irelan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Cardiac & Cardiovascular Systems

IKKβ inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury

Nancy C. Moss et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)

Article Biochemistry & Molecular Biology

IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

Dung-Fang Lee et al.

Article Pharmacology & Pharmacy

Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IκB kinase inhibitors

Robert Newton et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Article Dermatology

Topical application with a new NF-κB inhibitor improves atopic dermatitis in NC/NgaTnd mice

Akane Tanaka et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)

Article Biochemistry & Molecular Biology

Interleukin-1-induced NF-κB activation is NEMO-dependent but does not require IKKβ

Laura A. Solt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Rheumatology

Use of molecular Imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis

Elena S. Izmailova et al.

ARTHRITIS AND RHEUMATISM (2007)

Article Cardiac & Cardiovascular Systems

Inhibition of NF-kappa B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction

Yasuyuki Onai et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)

Review Oncology

Regulating the p53 pathway:: in vitro hypotheses, in vivo veritas

Franck Toledo et al.

NATURE REVIEWS CANCER (2006)

Article Biochemistry & Molecular Biology

Dimerization of the IκB kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-κB activity

Ralf B. Marienfeld et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Review Biochemistry & Molecular Biology

IκB kinase complexes:: gateways to NF-κB activation and transcription

Claus Scheidereit

ONCOGENE (2006)

Article Oncology

Nuclear factor-κB maintains TRAIL resistance in human pancreatic cancer cells

Sanaz Khanbolooki et al.

MOLECULAR CANCER THERAPEUTICS (2006)

Article Biochemistry & Molecular Biology

Regulation of IκB kinase (IKK) complex by IKKγ-dependent phosphorylation of the T-loop and C terminus of IKKβ

Beth Schomer-Miller et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Critical Care Medicine

A novel IκB kinase-β inhibitor ameliorates bleomycin-induced pulmonary fibrosis in mice

M Inayama et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Article Multidisciplinary Sciences

Identification of 14-3-3σ mutation causing cutaneous abnormality in repeated-epilation mutant mouse

QT Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Critical Care Medicine

Iκ-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma

MA Birrell et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

Article Biochemistry & Molecular Biology

IκB kinase α regulates subcellular distribution and turnover of cyclin D1 by phosphorylation

YT Kwak et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

MCT Hu et al.

Article Multidisciplinary Sciences

IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium

LJ Egan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Medicine, Research & Experimental

Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance

M Röhl et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Article Biochemistry & Molecular Biology

Protein phosphatase 2Cβ association with the IκB kinase complex is involved in regulating NF-κB activity

S Prajapati et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Cell Biology

Signaling to NF-κB

MS Hayden et al.

GENES & DEVELOPMENT (2004)

Article Biochemistry & Molecular Biology

Inhibition of NF-κB activation by peptides targeting NF-κB essential modulator (NEMO) oligomerization

F Agou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

IκB kinase β phosphorylates Dok1 serines in response to TNF, IL-1, or γ radiation

SH Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

IκB kinase is an essential component of the Tp12 signaling pathway

M Waterfield et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Inhibition of IκB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury

Y Onai et al.

CARDIOVASCULAR RESEARCH (2004)

Article Biochemistry & Molecular Biology

A novel ubiquitin-like domain in IκB kinase β is required for functional activity of the kinase

MJ May et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Immunology

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation

M Thome

NATURE REVIEWS IMMUNOLOGY (2004)

Article Biochemistry & Molecular Biology

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

T Ishitani et al.

EMBO JOURNAL (2003)

Article Multidisciplinary Sciences

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB

TR Brummelkamp et al.

NATURE (2003)

Article Immunology

TCR-induced NF-κB activation:: a crucial role for Carma1, Bcl10 and MALT1

M Thome et al.

TRENDS IN IMMUNOLOGY (2003)

Article Multidisciplinary Sciences

A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression

V Anest et al.

NATURE (2003)

Article Biochemistry & Molecular Biology

Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation

S Tegethoff et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Serine phosphorylation of insulin receptor substrate 1 by inhibitor κB kinase complex

ZG Gao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Characterization of the IκB-kinase NEMO binding domain

MJ May et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Biochemistry & Molecular Biology

IKKα, IKKβ, and NEMO/IKKγ are each required for the NF-κB-mediated inflammatory response program

X Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Immunology

BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells

E Claudio et al.

NATURE IMMUNOLOGY (2002)

Article Biochemistry & Molecular Biology

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAG-3/TRAM-1) coactivator activity by IκB kinase

RC Wu et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism

CM Liu et al.

Article Biochemistry & Molecular Biology

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

GQ Chen et al.

MOLECULAR CELL (2002)

Article Biochemistry & Molecular Biology

Regulation of β-catenin function by the IκB kinases

C Lamberti et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Multidisciplinary Sciences

Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway

U Senftleben et al.

SCIENCE (2001)

Article Multidisciplinary Sciences

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

C Wang et al.

NATURE (2001)

Article Immunology

The essential role of MEKK3 in TNF-induced NF-κB activation

JH Yang et al.

NATURE IMMUNOLOGY (2001)

Article Multidisciplinary Sciences

IKKα controls formation of the epidermis independently of NF-κB

YL Hu et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

D Bech-Otschir et al.

EMBO JOURNAL (2001)

Article Genetics & Heredity

Mekk3 is essential for early embryonic cardiovascular development

JH Yang et al.

NATURE GENETICS (2000)