Journal
IMMUNOLOGICAL REVIEWS
Volume 243, Issue -, Pages 91-98Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1600-065X.2011.01052.x
Keywords
antiviral innate immunity; type I interferon; RIG-I-like receptors; non-self RNA
Categories
Ask authors/readers for more resources
Viral infection results in the generation of non-self RNA species in the cells, which is recognized by retinoic acid inducible gene-I-like receptors (RLRs), and initiates innate antiviral responses, including the production of proinflammatory cytokines and type I interferon. In this review, we summarize reports on virus-specificity of RLRs, structures of non-self RNA patterns, structural biology of RLRs, and the signaling adapter molecules involved in antiviral innate immunity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available