Related references
Note: Only part of the references are listed.Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells
Pietro Luigi Poliani et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Clues to immune tolerance: the monogenic autoimmune syndromes
Michael Waterfield et al.
YEAR IN HUMAN AND MEDICAL GENETICS: NEW TRENDS IN MENDELIAN GENETICS (2010)
Aire's Partners in the Molecular Control of Immunological Tolerance
Jakub Abramson et al.
CELL (2010)
Regulatory T cell defect in APECED patients is associated with loss of naive FOXP3+ precursors and impaired activated population
Sini M. Laakso et al.
JOURNAL OF AUTOIMMUNITY (2010)
Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
Yumiko Nishikawa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin
Nichole M. Danzl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
Jarish N. Cohen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
Anne L. Fletcher et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
An Autoimmune Response to Odorant Binding Protein 1a Is Associated with Dry Eye in the Aire-Deficient Mouse
Jason J. DeVoss et al.
JOURNAL OF IMMUNOLOGY (2010)
Diversity of TCRs on Natural Foxp3+ T Cells in Mice Lacking Aire Expression
Danielle Daniely et al.
JOURNAL OF IMMUNOLOGY (2010)
Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
Andrea J. White et al.
JOURNAL OF IMMUNOLOGY (2010)
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
Kajsa Wing et al.
NATURE IMMUNOLOGY (2010)
Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance
Maria Hinterberger et al.
NATURE IMMUNOLOGY (2010)
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3
Andrew S. Koh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity
Lih-Yun Hsu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
Christian Koble et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity
Mireia Guerau-de-Arellano et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Ablation and Regeneration of Tolerance-Inducing Medullary Thymic Epithelial Cells after Cyclosporine, Cyclophosphamide, and Dexamethasone Treatment
Anne L. Fletcher et al.
JOURNAL OF IMMUNOLOGY (2009)
Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes
Linda Yip et al.
NATURE IMMUNOLOGY (2009)
DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity
Ingrid Liiv et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
Tonis Org et al.
EMBO REPORTS (2008)
PHD finger of autoimmune regulator An epigenetic link between the histone modifications and tissue-specific antigen expression in thymus
Giovanna Musco et al.
EPIGENETICS (2008)
The cytokine RANKL produced by positively selected thymocytes Fosters medullary thymic epithelial cells that express autoimmune regulator
Yu Hikosaka et al.
IMMUNITY (2008)
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity
Magali Irla et al.
IMMUNITY (2008)
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
Taishin Akiyama et al.
IMMUNITY (2008)
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
Maureen A. Su et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance
Masashi Yano et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Effector mechanisms of the autoimmune syndrome in the murine model of Autoimmune Polyglandular Syndrome Type 1
Jason J. DeVoss et al.
JOURNAL OF IMMUNOLOGY (2008)
A specific anti-Aire antibody reveals Aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery
Francois-Xavier Hubert et al.
JOURNAL OF IMMUNOLOGY (2008)
Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
Jens Derbinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Deletional tolerance mediated by extrathymic Aire-expressing cells
James M. Gardner et al.
SCIENCE (2008)
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity
Brian J. Ferguson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions
Owen M. Siggs et al.
IMMUNITY (2007)
AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
Irena Oven et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected
Emily S. Venanzi et al.
JOURNAL OF IMMUNOLOGY (2007)
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
Daniel Gray et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets
Jamie Wong et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes
Lisa A. Nichols et al.
JOURNAL OF IMMUNOLOGY (2007)
The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function
Qing-Guo Ruan et al.
JOURNAL OF IMMUNOLOGY (2007)
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
Katharina Aschenbrenner et al.
NATURE IMMUNOLOGY (2007)
Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation
Geoffrey O. Gillard et al.
JOURNAL OF IMMUNOLOGY (2007)
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
Je-Wook Lee et al.
NATURE IMMUNOLOGY (2007)
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
Jeong M. Kim et al.
NATURE IMMUNOLOGY (2007)
A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Eliisa Kekalainen et al.
JOURNAL OF IMMUNOLOGY (2007)
Zoned out: Functional mapping of stromal signaling microenvironments in the thymus
Howard T. Petrie et al.
ANNUAL REVIEW OF IMMUNOLOGY (2007)
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen
Jason DeVoss et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice
S Niki et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Linking signalling pathways, thymic stroma integrity and autoimmunity
J Derbinski et al.
TRENDS IN IMMUNOLOGY (2005)
Modifier loci condition autoimmunity provoked by Aire deficiency
WY Jiang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Cooperative activation of transcription by autoimmune regulator AIRE and CBP
J Pitkänen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
The cellular mechanism of Aire control of T cell tolerance
MS Anderson et al.
IMMUNITY (2005)
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
J Derbinski et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Chromosomal clustering of genes controlled by the aire transcription factor
JB Johnnidis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mapping DNA-binding domains of the autoimmune regulator protein
S Purohit et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of aire-deficient mice
N Kuroda et al.
JOURNAL OF IMMUNOLOGY (2005)
Autoimmune polyendocrinopathy syndrome type 1 (APS1) and AIRE gene: New views on molecular basis of autoimmunity
P Peterson et al.
JOURNAL OF AUTOIMMUNITY (2005)
Toll-like receptor control of the adaptive immune responses
A Iwasaki et al.
NATURE IMMUNOLOGY (2004)
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
CS Hsieh et al.
IMMUNITY (2004)
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
AM Gallegos et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
A Liston et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
N Sakaguchi et al.
NATURE (2003)
Thymic medullary epithelial cell differentiation thymocyte emigration, and the control of autoimmunity require lymphoepithelial cross talk via LTβR
T Boehm et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Aire regulates negative selection of organ-specific T cells
A Liston et al.
NATURE IMMUNOLOGY (2003)
Projection of an immunological self shadow within the thymus by the aire protein
MS Anderson et al.
SCIENCE (2002)
Lineage plasticity and commitment in T-cell development
EV Rothenberg et al.
IMMUNOLOGICAL REVIEWS (2002)
Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells
J Gill et al.
NATURE IMMUNOLOGY (2002)
Inactivation of Notch2 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ lineage thymocytes
A Wolfer et al.
IMMUNITY (2002)
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
C Ramsey et al.
HUMAN MOLECULAR GENETICS (2002)
T cell receptor excision circle assessment of thymopoiesis in aging mice
GD Semposski et al.
MOLECULAR IMMUNOLOGY (2002)
Expression of AIRE gene in peripheral monocyte/dendritic cell lineage
K Kogawa et al.
IMMUNOLOGY LETTERS (2002)
The autoimmune regulator (AIRE) is a DNA-binding protein
PG Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
J Derbinski et al.
NATURE IMMUNOLOGY (2001)
CREB-binding protein and p300 in transcriptional regulation
N Vo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
MS Jordan et al.
NATURE IMMUNOLOGY (2001)
Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
S Zuklys et al.
JOURNAL OF IMMUNOLOGY (2000)
Mutations in the AIRE gene:: Effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein
P Björses et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
L Klein et al.
NATURE MEDICINE (2000)
Share Paper
