Related references
Note: Only part of the references are listed.Preclinical Characterization of Naturally Occurring Polyketide Cyclophilin Inhibitors from the Sanglifehrin Family
Matthew A. Gregory et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Safety, pharmacokinetics, and antiviral activity of the cyclophilin inhibitor NIM811 alone or in combination with pegylated interferon in HCV-infected patients receiving 14 days of therapy
Eric Lawitz et al.
ANTIVIRAL RESEARCH (2011)
Telaprevir Alone or With Peginterferon and Ribavirin Reduces HCV RNA in Patients With Chronic Genotype 2 but Not Genotype 3 Infections
Graham R. Foster et al.
GASTROENTEROLOGY (2011)
Treatment Failure and Resistance with Direct-Acting Antiviral Drugs Against Hepatitis C Virus
Jean-Michel Pawlotsky
HEPATOLOGY (2011)
Domain 3 of NS5A Protein from the Hepatitis C Virus Has Intrinsic α-Helical Propensity and Is a Substrate of Cyclophilin A
Dries Verdegem et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Hepatitis C Virus Genotypes in Clinical Specimens Tested at a National Reference Testing Laboratory in the United States
Jeffrey J. Germer et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2011)
Cyclophilin A Interacts with Domain II of Hepatitis C Virus NS5A and Stimulates RNA Binding in an Isomerase-Dependent Manner
Toshana L. Foster et al.
JOURNAL OF VIROLOGY (2011)
NEW HEPATITIS C THERAPIES IN CLINICAL DEVELOPMENT
Johannes Vermehren et al.
EUROPEAN JOURNAL OF MEDICAL RESEARCH (2011)
Mechanism of Resistance of Hepatitis C Virus Replicons to Structurally Distinct Cyclophilin Inhibitors
Xiaoling Puyang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes
Udayan Chatterji et al.
JOURNAL OF GENERAL VIROLOGY (2010)
HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors
Udayan Chatterji et al.
JOURNAL OF HEPATOLOGY (2010)
The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A
Helen Waller et al.
JOURNAL OF VIROLOGICAL METHODS (2010)
Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
Fiona Fernandes et al.
PLOS ONE (2010)
DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A
Lotte Coelmont et al.
PLOS ONE (2010)
Multiple cyclophilins involved in different cellular pathways mediate HCV replication
L. Alex Gaither et al.
VIROLOGY (2010)
A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach
Feng Yang et al.
PLOS PATHOGENS (2010)
Review: New direct-acting antivirals in the development for hepatitis C virus infection
Paul J. Pockros
Therapeutic Advances in Gastroenterology (2010)
Development of novel antiviral therapies for hepatitis C virus
Kai Lin
VIROLOGICA SINICA (2010)
Identification of cellular and viral factors related to anti-hepatitis C virus activity of cyclophilin inhibitor
Kaku Goto et al.
CANCER SCIENCE (2009)
Cyclophilin Inhibitors
Philippe A. Gallay
CLINICS IN LIVER DISEASE (2009)
Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B
Xavier Hanoulle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication
Udayan Chatterji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Critical Role of Cyclophilin A and Its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the Hepatitis C Virus Replication Complex
Zhe Liu et al.
JOURNAL OF VIROLOGY (2009)
Protease and polymerase inhibitors for the treatment of hepatitis C
Tarik Asselah et al.
LIVER INTERNATIONAL (2009)
Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics
Artur Kaul et al.
PLOS PATHOGENS (2009)
Emerging drugs for hepatitis C
Vincent Soriano et al.
EXPERT OPINION ON EMERGING DRUGS (2008)
The cyclophilin inhibitor debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus
Robert Flisiak et al.
HEPATOLOGY (2008)
Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro
Feng Yang et al.
JOURNAL OF VIROLOGY (2008)
Current and future management of chronic hepatitis C infection
T. J. S. Cross et al.
POSTGRADUATE MEDICAL JOURNAL (2008)
Sensitivity of hepatitis C virus to cyclosporine a depends on nonstructural proteins NS5A and NS5B
Fiona Fernandes et al.
HEPATOLOGY (2007)
Characterization of hepatitis c virus subgenomic replicon resistance to cyclosporine in vitro
John M. Robida et al.
JOURNAL OF VIROLOGY (2007)
Epidemiology of hepatitis C virus infection
Miriam J. Alter
WORLD JOURNAL OF GASTROENTEROLOGY (2007)
Cyclophilin inhibitors in hepatitis C viral infection
Robert Flisiak et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
NIM811, a cyclophilin inhibitor, exhibits potent in vitro activity against hepatitis C virus alone or in combination with alpha interferon
Sue Ma et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
Gregory L. Armstrong et al.
ANNALS OF INTERNAL MEDICINE (2006)
Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811
K Goto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Diverse effects of cyclosporine on hepatitis C virus strain replication
N Ishii et al.
JOURNAL OF VIROLOGY (2006)
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro
J Paeshuyse et al.
HEPATOLOGY (2006)
Treating viral hepatitis C: Efficacy, side effects, and complications
M. P. Manns et al.
GUT (2006)
American Gastroenterological Association technical review on the management of hepatitis C
JL Dienstag et al.
GASTROENTEROLOGY (2006)
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
P Simmonds et al.
HEPATOLOGY (2005)
Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins
M Nakagawa et al.
GASTROENTEROLOGY (2005)
Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine
J Colgan et al.
JOURNAL OF IMMUNOLOGY (2005)
Global epidemiology of hepatitis C virus infection
CW Shepard et al.
LANCET INFECTIOUS DISEASES (2005)
Comparing the public health burden of chronic hepatitis C and HIV infection in France
S Deuffic-Burban et al.
JOURNAL OF HEPATOLOGY (2004)
Specific inhibition of hepatitis C virus replication by cyclosporin A
M Nakagawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Projecting future complications of chronic hepatitis C in the United States
GL Davis et al.
LIVER TRANSPLANTATION (2003)
Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes
K Watashi et al.
HEPATOLOGY (2003)
Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity
Y Shirota et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells
D Braaten et al.
EMBO JOURNAL (2001)
Share Paper
