4.3 Article

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules

Journal

IMMUNOGENETICS
Volume 64, Issue 6, Pages 455-460

Publisher

SPRINGER
DOI: 10.1007/s00251-012-0599-z

Keywords

Celiac disease; Gluten; Tcell; Epitopes; HLA-DQ2; HLA-DQ8

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Celiac disease is caused by an abnormal intestinal T-cell response to gluten proteins of wheat, barley and rye. Over the last few years, a number of gluten T-cell epitopes restricted by celiac disease associated HLA-DQ molecules have been characterized. In this work, we give an overview of these epitopes and suggest a comprehensive, new nomenclature.

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