Journal
IMMUNITY
Volume 41, Issue 5, Pages 679-681Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2014.11.004
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Immunotherapy is revolutionizing the treatment of cancer patients, but the molecular basis for tumor immunogenicity is unclear. In this issue of Immunity, Deng et al. (2014) and Woo et al. ( 2014) provide evidence suggesting that dendritic cells detect DNA from tumor cells via the STING-mediated, cytosolic DNA sensing pathway.
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