4.8 Editorial Material

T-bet Orchestrates CD8αα IEL Differentiation

Journal

IMMUNITY
Volume 41, Issue 2, Pages 169-171

Publisher

CELL PRESS
DOI: 10.1016/j.immuni.2014.08.003

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Funding

  1. Intramural NIH HHS [ZIA BC011431-02] Funding Source: Medline

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Very little is known about the transcription factor network that regulates the development of intestinal intraepithelial lymphocytes (IELs). In this issue of Immunity, Klose et al. (2014b) and Reis et al. (2014) demonstrate an essential role for T-bet in regulating the CD8 alpha alpha IEL differentiation program.

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