4.8 Editorial Material

JAK's SOCS: A Mechanism of Inhibition

Journal

IMMUNITY
Volume 36, Issue 2, Pages 157-159

Publisher

CELL PRESS
DOI: 10.1016/j.immuni.2012.01.010

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SOCS1 and SOCS3 are specific inhibitors for JAK tyrosine kinases. In this issue of Immunity, Babon et al. (2012) discovered the inhibition mechanism of SOCS3 by employing nuclear magnetic resonance and classical enzyme kinetics.

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