Journal
IMMUNITY
Volume 37, Issue 5, Pages 759-761Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2012.10.012
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Funding
- NIAID NIH HHS [F32 AI098383] Funding Source: Medline
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What does it take to make a regulatory T (Treg) cell? In this issue of Immunity, Ohkura et al. show that Treg-cell-specific CpG hypomethylation and Foxp3 expression are independent events required for Treg cell development, stability, and full suppressive activity.
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