Journal
IMMUNITY
Volume 34, Issue 5, Pages 651-664Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2011.05.001
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Funding
- Cancer Research UK
- UCL
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C-type lectin receptors (CLRs) comprise a heterogeneous group of transmembrane proteins. Many of them are expressed in myeloid cells and signal in response to pathogen-derived or self ligands to initiate or regulate cell activation. Here, we review the properties of myeloid CLRs, highlighting how their signaling function is coordinated with that of other innate receptor families to control immunity to infection.
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