Journal
IMMUNITY
Volume 34, Issue 4, Pages 453-455Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2011.04.001
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Funding
- NIAID NIH HHS [P01 AI070167-01, P01 AI070167] Funding Source: Medline
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Foreign DNA activates the innate immune response through Toll-like receptor 9 (TLR9). In this issue of Immunity, Park et al. (2011) present evidence that granulin is a cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.
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