Journal
IMMUNITY
Volume 31, Issue 2, Pages 178-180Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2009.08.005
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Funding
- NIAID NIH HHS [R01 AI017672-20, R01 AI017672, R37 AI017672, R01 AI081675-25, R01 AI081675] Funding Source: Medline
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The functions of T lymphocytes are regulated by transcription factors controlling gene expression. Three studies in this issue of Immunity (Kallies et al., 2009; Rutishauser et al., 2009; Shin et al., 2009) indicate that the transcriptional repressor Blimp-1 promotes the development of short-lived effector cells and regulates clonal exhaustion.
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