4.3 Article

Cerium fluoride nanoparticles protect cells against oxidative stress

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ELSEVIER
DOI: 10.1016/j.msec.2015.01.094

Keywords

Cerium fluoride nanoparticles; Terbium doped CeF3; Luminescence; Living cells; Virus; Oxidative stress; Toxicity

Funding

  1. Russian Scientific Foundation [14-13-01373]

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A novel facile method of non-doped and fluorescent terbium-doped cerium fluoride stable aqueous sols synthesis is proposed. Intense green luminescence of CeF3:Tb nanoparticles can be used to visualize these nanoparticles' accumulation in cells using confocal laser scanning microscopy. Cerium fluoride nanoparticles are shown for the first time to protect both organic molecules and living cells from the oxidative action of hydrogen peroxide. Both non-doped and terbium-doped CeF3 nanopaiticles are shown to provide noteworthy protection to cells against the vesicular stomatitis virus. (C) 2015 Elsevier B.V. All rights reserved.

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