Journal
IEEE TRANSACTIONS ON PLASMA SCIENCE
Volume 42, Issue 12, Pages 3760-3764Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TPS.2014.2353659
Keywords
Cancer therapy; non-thermal atmospheric pressure plasma; and plasma-activated medium
Categories
Funding
- Knowledge Cluster Initiative Second Stage-Tokai Region Nanotechnology Manufacturing Cluster
- [24108002]
- [24108008]
- Grants-in-Aid for Scientific Research [25870307, 25860292, 24108001] Funding Source: KAKEN
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We have been developing novel ultrahigh density atmospheric pressure plasma sources and succeeded in the selective killing ovarian cancer cells against normal ones. Furthermore, we have found out the plasma- activated medium (PAM) also killed glioblastoma brain tumor cells selectively against normal ones and the chemical products in the PAM have long lifetime healing effects. To clarify the mechanism, interactions of plasma with the organism and the medium where the organism belongs were investigated on the viewpoint of intracellular molecular mechanism.
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