4.5 Article

Carbon nanotube fibers are compatible with mammalian cells and neurons

Journal

IEEE TRANSACTIONS ON NANOBIOSCIENCE
Volume 7, Issue 1, Pages 11-14

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TNB.2008.2000144

Keywords

biocompatibility; carbon nanotubes; cell adhesion; neurons

Funding

  1. NIBIB NIH HHS [R21EB002889] Funding Source: Medline

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We demonstrate the biocompatibility of carbon nanotube fibers (CNFs) fabricated from single-wall carbon nanotubes. Produced by a particle-coagulation spinning process, CNFs are hair-like conductive microwires, which uniquely combine properties of porous nanostructured scaffolds, high-area electrodes, and permeable microfluidic conduits. We report that CNFs are nontoxic and support the attachment, spreading, and growth of mammalian cells and the extension of processes from neurons in vitro. Our findings suggest that CNF may be employed for an electrical interfacing of nerve cells and external devices.

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