Journal
MATERIALS LETTERS
Volume 160, Issue -, Pages 343-346Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2015.07.042
Keywords
Electrospinning setup; Aligned fiber; Nanometer diameter; Controllable thickness; Polymer; Fiber technology
Funding
- National Natural Science Foundation of China [31200724]
- China Postdoctoral Science Foundation [2014M560986]
- Shenzhen Peacock Plan [KQCX20130628155525051]
- Cross Scientific Research Innovation Fund of Graduate School at Shenzhen of Tsinghua University [JC20140005]
- Projects of Basic Research of Shenzhen [JCYJ 20140509172959988]
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Electrospinning is a popular nanotechnology used to produce fibrous scaffolds from a wide range of materials. For tissue regeneration and bioengineering applications, there is a growing interest in fabricating tailored 3D scaffolds with a complex tissue-like structure, i.e., nanometer diameter, aligned fibers and controllable thickness that may be suitable for specific organs and tissues. However, conventional electrospinning techniques can only produce either 2D aligned nanofibrous structures with limited thickness or 3D fibrous scaffolds with disordered fibrous structures. In this study, a novel electrospinning setup using a parallel double thin plate collector device and a separate fiber removal device was developed to generate 3D electrospun scaffolds with aligned nanofibers and controllable thickness. As a demonstration, the formation mechanism of the ordered fibrous structure was analyzed, and polyvinyl alcohol (PVA) was processed into fibrous scaffolds. The nanofibrous membranes possessed a high alignment degree with approximately 76% of the fibers within +/-5 degrees and tailored thicknesses from 69.6 to 1144.9 mu m. Crown Copyright (C) 2015 Published by Elsevier B.V. All rights reserved.
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