Journal
IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 31, Issue 5, Pages 1154-1162Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2012.2187460
Keywords
Heterogeneous speed of sound; model-based reconstruction; optoacoustic tomography; photoacoustic tomography
Categories
Funding
- German Research Foundation (DFG) [RA 1848/1]
- ERC
- Medizin Technik BMBF
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Optoacoustic tomography has recently demonstrated powerful performance in small animal imaging and initial clinical trials in terms of the high spatial resolution, versatile contrast, and dynamic imaging capabilities it can provide. Yet, the current optoacoustic image reconstruction methods are usually based on inaccurate forward modelling approaches or otherwise demand a high computational cost, which imposes certain practical limitations and hinders image quantification. Herein, we introduce a new method for accelerating optoacoustic reconstructions, based on angular image discretization of the forward model solution. The method is particularly suitable for accurate image reconstruction with arbitrary meshes and space-dependent resolution, while it can also readily account for small speed of sound variations without compromising the calculation speed. It is further anticipated that the new approach will greatly facilitate development of high performance 3-D optoacoustic reconstruction methods.
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