Journal
IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 30, Issue 2, Pages 401-408Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2010.2081683
Keywords
Acoustic mismatch; back-projection algorithm; optoacoustic tomography; statistical correction
Categories
Funding
- German Research Foundation (DFG) [RA 1848/1]
- ERC
- Medizin Technik BMBF
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A method is presented to reduce artefacts produced in optoacoustic tomography images due to internal reflection or scattering of the acoustic waves. It is based on weighting the tomographic contribution of each detector with the probability that a signal affected by acoustic mismatches is measured at that position. The correction method does not require a priori knowledge of the acoustic or optical properties of the imaged sample. Performance tests were made with agar phantoms that included air gaps for mimicking strong acoustic reflections as well as with an acoustically heterogeneous adult Zebrafish. The results obtained with the method proposed show a clear reduction of the artefacts with respect to the original images reconstructed with filtered back-projection algorithm. This performance is directly related to in vivo small animal imaging applications involving imaging in the presence of bones, lungs, and other highly mismatched organs.
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