4.4 Article

Synthesizing Distributions of Magnetic Nanoparticles for Clinical Hyperthermia

Journal

IEEE TRANSACTIONS ON MAGNETICS
Volume 48, Issue 2, Pages 263-266

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMAG.2011.2174340

Keywords

Finite-element field analysis; magnetic fluid hyperthermia; magnetic nanoparticles; optimization

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An automated procedure based on evolutionary computation and Finite Element Analysis (FEA) is proposed to synthesize the optimal distribution of nanoparticles (NPs) in multi-site injection for a Magnetic Fluid Hyperthermia (MFH) therapy. In particular a bi-objective formulation of the synthesis problem is considered taking into account both surface and volume temperature distribution in the tumor region.

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