Journal
MARINE DRUGS
Volume 13, Issue 9, Pages 5750-5766Publisher
MDPI
DOI: 10.3390/md13095750
Keywords
astaxanthin; oxidative stress; inflammation; apoptosis; neuroprotection; neurological diseases
Categories
Funding
- National Natural Science Foundation of China [81171096, 81371433]
- Public Technology Application Research Project of Zhejiang Province [2014C33G2010288]
Ask authors/readers for more resources
Neurological diseases, which consist of acute injuries and chronic neurodegeneration, are the leading causes of human death and disability. However, the pathophysiology of these diseases have not been fully elucidated, and effective treatments are still lacking. Astaxanthin, a member of the xanthophyll group, is a red-orange carotenoid with unique cell membrane actions and diverse biological activities. More importantly, there is evidence demonstrating that astaxanthin confers neuroprotective effects in experimental models of acute injuries, chronic neurodegenerative disorders, and neurological diseases. The beneficial effects of astaxanthin are linked to its oxidative, anti-inflammatory, and anti-apoptotic characteristics. In this review, we will focus on the neuroprotective properties of astaxanthin and explore the underlying mechanisms in the setting of neurological diseases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available