Journal
IEEE SENSORS JOURNAL
Volume 10, Issue 1, Pages 64-70Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/JSEN.2009.2035213
Keywords
Exhaled breath condensate; glucose; high electron mobility transistors (HEMTs); pH
Funding
- National Science Foundation [CTS-0301178, DMR 0703340]
- Office of Naval Research
- State of Florida, Center of Excellence for Nano-Bio Applications
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Peltier element cooling of ungated AlGaN/GaN high electron mobility transistors (HEMTs) is shown to be an effective method for condensing exhaled breath, enabling the measurement of the pH and glucose of the exhaled breath condensate (EBC). By comparison with standard solutions, the current change measured in the HEMTs with EBC shows that the sensitivity of the glucose detection is lower than the glucose concentration in the EBC of healthy human subjects and the pH of the condensate from the exhaled breath is within the range of 7-8, typical of that for human blood. The HEMT sensors can be integrated into a wireless data transmission system that allows for remote monitoring. Details of the transmitter and receiver design for the transmission system are given. Our work demonstrates the possibility of using AlGaN/GaN HEMTs for extended investigations of airway pathology without the need for clinical visits.
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