Journal
MACROMOLECULAR RAPID COMMUNICATIONS
Volume 36, Issue 14, Pages 1306-1321Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.201500117
Keywords
supramolecular nanoparticles; fluorescence; -conjugated small molecules; self-assembly; biological applications
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Funding
- HTSM through STW [12859-FluNanoPart]
- Ministry of Education, Culture and Science [024.001.035]
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Since the development of supramolecular chemical biology, self-organised nano-architectures have been widely explored in a variety of biomedical applications. Functionalized synthetic molecules with the ability of non-covalent assembly in an aqueous environment are typically able to interact with biological systems and are therefore especially interesting for their use in theranostics. Nanostructures based on -conjugated oligomers are particularly promising as theranostic platforms as they bear outstanding photophysical properties as well as drug loading capabilities. This Feature Article provides an overview on the recent advances in the self-assembly of intrinsically fluorescent nanoparticles from -conjugated small molecules such as fluorene or perylene based chromophores for biomedical applications.
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