Related references
Note: Only part of the references are listed.Model-Directed Engineering of Difficult-to-Express'' Monoclonal Antibody Production by Chinese Hamster Ovary Cells
Leon P. Pybus et al.
BIOTECHNOLOGY AND BIOENGINEERING (2014)
Predicting the Expression of Recombinant Monoclonal Antibodies in Chinese Hamster Ovary Cells Based on Sequence Features of the CDR3 Domain
Leon P. Pybus et al.
BIOTECHNOLOGY PROGRESS (2014)
Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance
Pete Gagnon et al.
JOURNAL OF CHROMATOGRAPHY A (2014)
Optimisation of the foot-and-mouth disease virus 2A co-expression system for biomedical applications
Ekaterina Minskaia et al.
BMC BIOTECHNOLOGY (2013)
Control of IgG LC:HC ratio in stably transfected CHO cells and study of the impact on expression, aggregation, glycosylation and conformational stability
Steven C. L. Ho et al.
JOURNAL OF BIOTECHNOLOGY (2013)
Characterization and removal of aggregates formed by nonspecific interaction of IgM monoclonal antibodies with chromatin catabolites during cell culture production
Hui Theng Gan et al.
JOURNAL OF CHROMATOGRAPHY A (2013)
Comparison of Internal Ribosome Entry Site (IRES) and Furin-2A (F2A) for Monoclonal Antibody Expression Level and Quality in CHO Cells
Steven C. L. Ho et al.
PLOS ONE (2013)
An Internal Ribosome Entry Site (IRES) Mutant Library for Tuning Expression Level of Multiple Genes in Mammalian Cells
Esther Y. C. Koh et al.
PLOS ONE (2013)
Protein Coexpression Using FMDV 2A: Effect of Linker Residues
Ekaterina Minskaia et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Generation of monoclonal antibody-producing mammalian cell lines
Steven C. L. Ho et al.
PHARMACEUTICAL BIOPROCESSING (2013)
IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines
Steven C. L. Ho et al.
JOURNAL OF BIOTECHNOLOGY (2012)
2A Peptide-based, Lentivirus-mediated Anti-death Receptor 5 Chimeric Antibody Expression Prevents Tumor Growth in Nude Mice
Meng Li et al.
MOLECULAR THERAPY (2012)
2A peptides provide distinct solutions to driving stop-carry on translational recoding
Pamila Sharma et al.
NUCLEIC ACIDS RESEARCH (2012)
Flp and Cre expressed from Flp-2A-Cre and Flp-IRES-Cre transcription units mediate the highest level of dual recombinase-mediated cassette exchange
Rachelle P. Anderson et al.
NUCLEIC ACIDS RESEARCH (2012)
Impact of gene vector design on the control of recombinant monoclonal antibody production by chinese hamster ovary cells
Sarah L. Davies et al.
BIOTECHNOLOGY PROGRESS (2011)
High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice
Jin Hee Kim et al.
PLOS ONE (2011)
Combination of the 2A/furin technology with an animal component free cell line development platform process
Thomas Jostock et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Coexpression of double or triple copies of the rabies virus glycoprotein gene using a 'self-cleaving' 2A peptide-based replication-defective human adenovirus serotype 5 vector
Yeping Tan et al.
BIOLOGICALS (2010)
Cell Line-Specific Control of Recombinant Monoclonal Antibody Production by CHO Cells
Peter M. O'Callaghan et al.
BIOTECHNOLOGY AND BIOENGINEERING (2010)
Inhibition of 2A-mediated 'cleavage' of certain artificial polyproteins bearing N-terminal signal sequences
Pablo de Felipe et al.
BIOTECHNOLOGY JOURNAL (2010)
Vector Fragmentation: Characterizing Vector Integrity in Transfected Clones by Southern Blotting
Say Kong Ng et al.
BIOTECHNOLOGY PROGRESS (2010)
Development trends for human monoclonal antibody therapeutics
Aaron L. Nelson et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions
Mario A. Izidoro et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)
Mutated Polyadenylation Signals for Controlling Expression Levels of Multiple Genes in Mammalian Cells
Yuansheng Yang et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
A Study of Monoclonal Antibody-Producing CHO Cell Lines: What Makes a Stable High Producer?
Janet Chusainow et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
A Clone Screening Method Using mRNA Levels to Determine Specific Productivity and Product Quality for Monoclonal Antibodies
Christina J. Lee et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Dissection of a co-translational nascent chain separation event
Victoria A. Doronina et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity
Andrew D. Simmons et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition
S. Yang et al.
GENE THERAPY (2008)
Site-specific release of nascent chains from ribosomes at a sense codon
Victoria A. Doronina et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Analysis of IgG heavy chain to light chain ratio with mutant Encephalomyocarditis virus internal ribosome entry site
Jiandong Li et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2007)
Molecular analysis of successful cell line selection in transfected GS-NS0 myeloma cells
Louise M. Barnes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2007)
A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies
Jiandong Li et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2007)
Antibody production
John R. Birch et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
E unum pluribus:: multiple proteins from a self-processing polyprotein
P de Felipe et al.
TRENDS IN BIOTECHNOLOGY (2006)
On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells
S Schlatter et al.
BIOTECHNOLOGY PROGRESS (2005)
Stable antibody expression at therapeutic levels using the 2A peptide
JM Fang et al.
NATURE BIOTECHNOLOGY (2005)
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector
AL Szymczak et al.
NATURE BIOTECHNOLOGY (2004)
Kinetic model of BiP- and PDI-mediated protein folding and assembly
R González et al.
JOURNAL OF THEORETICAL BIOLOGY (2002)
Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs
M Hennecke et al.
NUCLEIC ACIDS RESEARCH (2001)
The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences
MLL Donnelly et al.
JOURNAL OF GENERAL VIROLOGY (2001)
Stabilized, long-term expression of heterodimeric proteins from tricistronic mRNA
C Mielke et al.
GENE (2000)
Share Paper
