Journal
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
Volume 14, Issue 1, Pages 198-205Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/JSTQE.2007.914738
Keywords
gene diagnostics; metallic nanostructures; nanoprobes; near-field detection; plasmonics; Raman; surface-enhanced Raman scattering (SERS)
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Funding
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB006201] Funding Source: NIH RePORTER
- NIBIB NIH HHS [R01 EB006201-04, R01 EB006201] Funding Source: Medline
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This paper provides an overview of the development and applications of plasmonics-active nanoprobes in biomedical diagnostics. Specific examples of detection techniques using surface-enhanced Raman scattering are presented to illustrate the usefulness and potential of the plasmonics nanoprobes for gene detection and nanobiosensing. The detection of specific target deoxyribonucleic acids sequences using a novel molecular sentinel nanoprobe method is presented and discussed in detail.
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