Journal
LUNG CANCER
Volume 89, Issue 3, Pages 223-231Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.lungcan.2015.06.018
Keywords
Mesothelioma; Treatment; Chemotherapy; Second line; Biological; Targeted treatment; Outcome; Meta-analysis
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After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression. We conducted a systematic review of the literature for the activity, effectiveness and toxicity of second line treatment. The results are presented according to the class of drugs: chemotherapy and targeted or biological agent. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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