Journal
LIPIDS IN HEALTH AND DISEASE
Volume 14, Issue -, Pages -Publisher
BMC
DOI: 10.1186/1476-511X-14-2
Keywords
Irisin; Obesity; Metabolic diseases
Funding
- Shanghai Shenkang Prevention Prog of Disease [SHDC12012303]
- Chinese Medical Association Fund [12020 550355]
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Irisin is a newly discovered exercise-mediated myokine which regulates energy metabolism and has been the subject of much recent research. Irisin plays an important role in metabolic diseases making it a potential new target to combat obesity and its associated disorders, such as T2DM. However, the results of several recent studies investigating the effects of irisin have been controversial. The present review will introduce the discovery of irisin, the role of irisin in metabolic disorders, possible mechanisms, and unanswered questions for future research.
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