Journal
HYPERTENSION
Volume 55, Issue 5, Pages 1075-1085Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/HYPERTENSIONAHA.110.150821
Keywords
FMD; endothelial function; reactive hyperemia; shear stress
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Funding
- National Institutes of Health [P01-HL-0918830]
- Tobacco-Related Disease Research Program [15RT-0100]
- Parker B. Francis Family Foundation
- American Heart Association [08535209N]
- Salt Lake City Veterans' Affairs Medical Center Geriatric Research, Education, and Clinical Center
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Developed in 1992, the flow-mediated dilation test is now the most commonly used noninvasive assessment of vascular endothelial function in humans. Since its inception, scientists have refined their understanding of the physiology, analysis, and interpretation of this measurement. Recently, a significant growth of knowledge has added to our understanding and implementation of this clinically relevant research methodology. Therefore, this tutorial provides timely insight into recent advances and practical information related to the ultrasonic assessment of vascular endothelial function in humans. (Hypertension. 2010;55:1075-1085.)
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