Journal
LEUKEMIA & LYMPHOMA
Volume 57, Issue 1, Pages 17-20Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/10428194.2015.1061191
Keywords
Patient outcomes; myelodysplastic syndromes; infographic; stem cell transplantation; causes of death
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The causes of death in patients with myelodysplastic syndromes (MDS) are diverse: infections, hemorrhage, complications of chronic anemia and repeated blood transfusions, and complications of progression to acute myeloid leukemia. Since most patients with MDS are diagnosed late in life, some individuals with MDS will succumb to an unrelated condition, such as one of the disorders that are common in geriatric populations. Currently, only a small proportion of patients with MDS - less than 5% - undergo allogeneic stem cell transplantation, a procedure that offers the only possibility of cure. This brief review summarizes outcomes for patients diagnosed with MDS using a pictographical format that illustrates both the challenges patients face and the pressing need for development of novel therapies, as well as highlighting the potential for increased use of allogeneic stem cell transplant. This informational graphic may be useful for teaching or in counseling certain patients.
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