Journal
HUMAN VACCINES
Volume 7, Issue 3, Pages 383-390Publisher
LANDES BIOSCIENCE
DOI: 10.4161/hv.7.3.14989
Keywords
Cowpea mosaic virus; chimaera; virus-like particles; Real-time PCR controls; pI adjustment
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Funding
- EU [KBBE-227056]
- Biotechnology and Biological Science Research Council (BBSRC)
- Marie Curie [MEST-CT-2005-019727]
- John Innes Foundation
- Biotechnology and Biological Sciences Research Council [BBS/E/J/000CA326, BBS/E/J/00000166] Funding Source: researchfish
- BBSRC [BBS/E/J/000CA326] Funding Source: UKRI
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Particles of cowpea mosaic virus (CPMV) have enjoyed considerable success as a means of presenting peptides for vaccine purposes. However, the existing technology has limitations in regard to the size and nature of the peptides which can be presented and has problems regarding bio-containment. Recent developments suggest ways by which these problems can be overcome, increasing the range of potential applications of CPMV-based particle technology.
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